Article

Mining for ions: diagnostic feature detection in MS/MS spectra of post-translationally modified peptides

2022-09-13

Abstract excerpt

Post-translational modifications (PTMs) are an area of great interest in proteomics, with a surge in methods to detect them in recent years. However, PTMs can introduce complexity into proteomics searches by fragmenting in unexpected ways. Detecting post-translational modifications in mass spectrometry-based proteomics traditionally relies on identifying ions shifted by the masses of the modifications. This presen...

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Literature Corpus work: 1469a8a5-353b-5a31-9603-2a5a80938026
DOI: 10.1101/2022.09.12.507594

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