Article
Impairment of lagging strand synthesis triggers the formation of a RuvABC substrate at replication forks.
The EMBO journal - 1 Feb 2001
Flores M J, Bierne H, Ehrlich S D, Michel B
Abstract excerpt
The holD gene codes for the psi subunit of the Escherichia coli DNA polymerase III holoenzyme, a component of the gamma complex clamp loader. A holD mutant was isolated for the first time in a screen for mutations that increase the frequency of tandem repeat deletions. In contrast to tandem repeat deletions in wild-type strains, deletion events stimulated by the holD mutation require RecA. They do not require...
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