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Article

ssb gene duplication restores the viability of ΔholC and ΔholD Escherichia coli mutants.

PLoS genetics - 1 Oct 2014

Duigou Stéphane, Silvain Maud, Viguera Enrique, Michel Bénédicte

Abstract excerpt

The HolC-HolD (χψ) complex is part of the DNA polymerase III holoenzyme (Pol III HE) clamp-loader. Several lines of evidence indicate that both leading- and lagging-strand synthesis are affected in the absence of this complex. The Escherichia coli ΔholD mutant grows poorly and suppressor mutation...

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Share to DNA Polymerase III
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Duplication

Share to Gene Expression Regulation, Bacterial

Share to SOS Response, Genetics

Share to Suppression, Genetic

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Source

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Identifiers

PMID: 25329071
DOI: 10.1371/journal.pgen.1004719
PMCID: PMC4199511

Genes

SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25329071-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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