Article
DNA repeat rearrangements mediated by DnaK-dependent replication fork repair.
Molecular cell - 3 Mar 2006
Goldfless Stephen J, Morag Aviv Segal, Belisle Kurt A, Sutera Vincent A, Lovett Susan T
Abstract excerpt
We propose that rearrangements between short tandem repeated sequences occur by errors made during a replication fork repair pathway involving a replication template switch. We provide evidence here that the DnaK chaperone of E. coli controls this template switch repair process. Mutants in dnaK are sensitive to replication fork damage and exhibit high expression of the SOS response, indicative of repair...
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