Article
Expression of natural killer receptor alleles at different Ly49 loci occurs independently and is regulated by major histocompatibility complex class I molecules.
The Journal of experimental medicine - 5 Feb 2001
Tanamachi D M, Hanke T, Takizawa H, Jamieson A M, Raulet D R
Abstract excerpt
Ly49 receptor genes are expressed by subsets of natural killer (NK) cells in an overlapping fashion, accounting for the capacity of NK subsets to attack host cells that have selectively downregulated self-major histocompatibility complex (MHC) class I molecules. It was shown previously that most NK cells express only one or the other allele of a given Ly49 gene, while a smaller population expresses both alleles....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.