Article
Allelic exclusion of Ly49-family genes encoding class I MHC-specific receptors on NK cells.
Nature - 27 Jul 1995
Held W, Roland J, Raulet D H
Abstract excerpt
An important feature of natural killer (NK) cell activity is the lysis of cells that have extinguished expression of some or all class I major histocompatibility (MHC) molecules. Accordingly, the Ly49A NK-cell antigen receptor has been shown to deliver an inhibitory signal to NK cells on encounte...
Topics
- Alleles
- Animals
- Antigens, Ly
- Base Sequence
- Cells, Cultured
- Cloning, Molecular
- DNA Primers
- Histocompatibility Antigens Class I
- Killer Cells, Natural
- Lectins, C-Type
- Membrane Glycoproteins
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Inbred CBA
- Molecular Sequence Data
- NK Cell Lectin-Like Receptor Subfamily A
- Receptors, Immunologic