Article
Mono-allelic Ly49 NK cell receptor expression.
Seminars in immunology - 1 Oct 1999
Held W, Kunz B, Ioannidis V, Lowin-Kropf B
Abstract excerpt
Each cell is equipped with two copies (alleles) of each autosomal gene. While the vast majority use both alleles, occasional genes are expressed from a single allele. The reason for mono-allelic expression is not always evident and can serve distinct purposes. First, it may facilitate the tight control over the dosage of certain gene products such as some growth factors and their receptors or X-linked genes....
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