Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Independent control of Ly49g alleles: implications for NK cell repertoire selection and tumor cell killing.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2004

Makrigiannis Andrew P, Rousselle Etienne, Anderson Stephen K

Abstract excerpt

A novel murine NK cell-reactive mAb, AT8, was generated. AT8 recognizes Ly49G from 129/J, BALB/c, and related mouse strains, but does not bind to Ly49G(B6). Costaining with AT8 and a Ly49G(B6)-restricted Ab (Cwy-3) provides the first direct evidence that Ly49G protein is expressed from both alleles on a significant proportion of NK cells from four different types of F(1) hybrid mice. The observed level of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Ly
Share to Cytotoxicity, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lectins, C-Type

Share to Mice, Inbred C3H

Share to Mice, Inbred CBA

Share to Receptors, Immunologic

Share to Receptors, KIR

Share to Spleen

Source

Identifiers

PMID: 14734717
DOI: 10.4049/jimmunol.172.3.1414

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Independent control of Ly49g alleles: implications for NK cell repertoire selection and tumor cell killing.PMID 14734717Read ↗

Expression of natural killer receptor alleles at different Ly49 loci occurs independently and is regulated by major histocompatibility complex class I molecules.Semantic proximity Read ↗

An allele-specific, stochastic gene expression process controls the expression of multiple Ly49 family genes and generates a diverse, MHC-specific NK cell receptor repertoire.Semantic proximity Read ↗

Ly49A allelic variation and MHC class I specificity.Semantic proximity Read ↗

H-2 allele specificity of the NK cell C-type lectin-like MHC class I receptor Ly49A visualized by soluble Ly49A tetramer.Semantic proximity Read ↗

Class I MHC-binding characteristics of the 129/J Ly49 repertoire.Semantic proximity Read ↗

Expression of the Ly49A gene in murine natural killer cell clones is predominantly but not exclusively mono-allelic.Semantic proximity Read ↗

Allelic variation in the ectodomain of the inhibitory Ly-49G2 receptor alters its specificity for allogeneic and xenogeneic ligands.Semantic proximity Read ↗

The alpha2 domain of H-2Dd restricts the allelic specificity of the murine NK cell inhibitory receptor Ly-49A.Semantic proximity Read ↗

The role of Ly49A and 5E6(Ly49C) molecules in hybrid resistance mediated by murine natural killer cells against normal T cell blasts.Semantic proximity Read ↗

Evidence for high bi-allelic expression of activating Ly49 receptors.Semantic proximity Read ↗

The NK2.1 receptor is encoded by Ly-49C and its expression is regulated by MHC class I alleles.Semantic proximity Read ↗

Ly49 receptors: evolution, genetic diversity, and impact on immunity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.