Article
Tof1p regulates DNA damage responses during S phase in Saccharomyces cerevisiae.
Genetics - 1 Feb 2001
Foss E J
Abstract excerpt
A tof1 mutant was recovered in a screen aimed at identifying genes involved specifically in the S phase branch of the MEC1-dependent DNA damage response pathway. The screen was based on the observation that mutants missing this branch are particularly dependent on the cell cycle-wide branch and, therefore, on RAD9, for surviving DNA damage. tof1 and rad9 conferred synergistic sensitivity to MMS, UV, and HU, and...
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