Article
S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe.
Genes & development - 1 Feb 1998
Lindsay H D, Griffiths D J, Edwards R J, Christensen P U, Murray J M, Osman F, Walworth N, Carr A M
Abstract excerpt
Checkpoints that respond to DNA structure changes were originally defined by the inability of yeast mutants to prevent mitosis following DNA damage or S-phase arrest. Genetic analysis has subsequently identified subpathways of the DNA structure checkpoints, including the reversible arrest of DNA...
Topics
- Cell Cycle Proteins
- Checkpoint Kinase 1
- Checkpoint Kinase 2
- DNA Damage
- DNA Replication
- Enzyme Activation
- Fungal Proteins
- Genes, Suppressor
- Hydroxyurea
- Mitosis
- Molecular Sequence Data
- Multigene Family
- Mutation
- Phosphoproteins
- Phosphorylation