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Article

Consequences of abnormal CDK activity in S phase.

Cell cycle (Georgetown, Tex.) - 1 Jan 2016

Anda Silje, Rothe Christiane, Boye Erik, Grallert Beáta

Abstract excerpt

Cyclin Dependent Kinases (CDKs) are important regulators of DNA replication. In this work we have investigated the consequences of increasing or decreasing the CDK activity in S phase. To this end we identified S-phase regulators of the fission yeast CDK, Cdc2, and used appropriate mutants to modulate Cdc2 activity. In fission yeast Mik1 has been thought to be the main regulator of Cdc2 activity in S phase....

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Identifiers

PMID: 26918805
DOI: 10.1080/15384101.2016.1152423
PMCID: PMC4889304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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