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Article

Coupling of Saccharomyces cerevisiae early meiotic gene expression to DNA replication depends upon RPD3 and SIN3.

Genetics - 1 Feb 2001

Lamb T M, Mitchell A P

Abstract excerpt

It has been established that meiotic recombination and chromosome segregation are inhibited when meiotic DNA replication is blocked. Here we demonstrate that early meiotic gene (EMG) expression is also inhibited by a block in replication. Since early meiotic genes are required to promote meiotic recombination and DNA division, the low expression of these genes may contribute to the block in meiotic progression....

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Identifiers

PMID: 11156977
DOI: 10.1093/genetics/157.2.545
PMCID: PMC1461525

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