Article
Positive control of yeast meiotic genes by the negative regulator UME6.
Molecular and cellular biology - 1 Jun 1995
Bowdish K S, Yuan H E, Mitchell A P
Abstract excerpt
The yeast meiotic activator IME1 stimulates transcription of many early meiotic genes. These genes share a 5' sequence called URS1. URS1 sites function as repression sites in cells that lack IME1; we show here that URS1 sites are weak activation sequences in cells that express IME1. Repression through URS1 sites is known to depend upon the URS1-binding protein UME6. We have identified a UME6 allele (previously...
Topics
- Alleles
- Base Sequence
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Meiosis
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Plasmids
- Repressor Proteins