Article
The conserved histone deacetylase Rpd3 and the DNA binding regulator Ume6 repress BOI1's meiotic transcript isoform during vegetative growth in Saccharomyces cerevisiae.
Molecular microbiology - 1 May 2015
Liu Yuchen, Stuparevic Igor, Xie Bingning, Becker Emmanuelle, Law Michael J, Primig Michael
Abstract excerpt
BOI1 and BOI2 are paralogs important for the actin cytoskeleton and polar growth. BOI1 encodes a meiotic transcript isoform with an extended 5'-untranslated region predicted to impair protein translation. It is, however, unknown how the isoform is repressed during mitosis, and if Boi1 is present during sporulation. By interpreting microarray data from MATa cells, MATa/α cells, a starving MATα/α control, and a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.