Article
Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease.
Gut - 1 Feb 2001
Hampe J, Lynch N J, Daniels S, Bridger S, Macpherson A J, Stokkers P, Forbes A, Lennard-Jones J E, Mathew C G, Curran M E, Schreiber S
Abstract excerpt
BACKGROUND AND AIMS: Genetic predisposition for inflammatory bowel disease (IBD) has been demonstrated by epidemiological and genetic linkage studies. Genetic linkage of IBD to chromosome 3 has been observed previously. A high density analysis of chromosome 3p was performed to confirm prior linkages and elucidate potential genetic associations. METHODS: Forty three microsatellite markers on chromosome 3 were...
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