Phenotype-stratified genetic linkage study demonstrates that IBD2 is an extensive ulcerative colitis locus.

doi:10.1111/j.1572-0241.2006.00451.x

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Article

Phenotype-stratified genetic linkage study demonstrates that IBD2 is an extensive ulcerative colitis locus.

The American journal of gastroenterology - 1 Mar 2006

Achkar Jean-Paul, Dassopoulos Themistocles, Silverberg Mark S, Tuvlin Jeffrey A, Duerr Richard H, Brant Steven R, Siminovitch Kathy, Reddy Deepa, Datta Lisa W, Bayless Theodore M, Zhang Leilei, Barmada M Michael, Rioux John D, Steinhart A Hillary, McLeod Robin S, Griffiths Anne M, Cohen Zane, Yang Huiying, Bromfield Gillian P, Schumm Phil, Hanauer Stephen B, Cho Judy H, Nicolae Dan L

Abstract excerpt

OBJECTIVES: The complete elucidation of genetic variants that contribute to inflammatory bowel disease (IBD) will likely include variants that increase risk to both Crohn's disease and ulcerative colitis as well as variants that increase risk for particular phenotypic subsets. The purpose of this study was to assess phenotypic subsets that contribute to the major IBD susceptibility loci. METHODS: This linkage...

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Identifiers

PMID: 16542294
DOI: 10.1111/j.1572-0241.2006.00451.x

Genes

NOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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