Article
Association of the TNF-alpha-308 (G-->A) polymorphism with self-reported history of childhood asthma.
Human genetics - 1 Dec 2000
Winchester E C, Millwood I Y, Rand L, Penny M A, Kessling A M
Abstract excerpt
Asthma is a complex disease involving genetic and environmental aetiology. The tumour necrosis factor-alpha (TNF-alpha) and angiotensin-converting enzyme (ACE) genes have been implicated in asthma pathogenesis. This study investigated the association of a G-308A variant of TNF-alpha and an insertion/deletion (I/D) variant of ACE with a self-reported history of childhood asthma, in two population groups. At...
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