Article
Association of G-308A TNF-alpha polymorphism with bronchial asthma in a North Indian population.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Dec 2005
Gupta Vikas, Sarin B C, Changotra Harish, Sehajpal P K
Abstract excerpt
Bronchial asthma is an inflammatory disorder in which genetic and environmental factors play an important role. Several susceptible genes have been identified using whole genome scan and candidate gene approaches. Tumor necrosis factor alpha, a pro-inflammatory cytokine, is one such gene that figures prominently in such investigations. The secreted levels of this cytokine are under genetic control and attributed...
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