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Article

Association of TNF haplotypes with asthma, serum IgE levels, and correlation with serum TNF-alpha levels.

American journal of respiratory cell and molecular biology - 1 Oct 2006

Sharma Shilpy, Sharma Amit, Kumar Sarvesh, Sharma Surendra K, Ghosh Balaram

Abstract excerpt

Both biochemical and genetic evidence have implicated the genes for TNF-alpha (TNFA) and lymphotoxin-alpha (LTA) in atopic asthma. Here, we report for the first time the association of their genotypes and haplotypes with atopic asthma in Indian populations. We genotyped seven single nucleotide polymorphisms, encompassing the two genes, in patients and control subjects in two independent cohorts. Serum TNF-alpha...

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Source

Identifiers

PMID: 16728705
DOI: 10.1165/rcmb.2006-0084OC

Genes

TNF
LTA

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