Article
Tumour necrosis factor α polymorphism (TNF-308α G/A) in association with asthma related phenotypes and air pollutants among children in KwaZulu-Natal.
Asian Pacific journal of allergy and immunology - 1 Sept 2016
Makamure Michelle T, Reddy Poovendhree, Chuturgoon Anil, Naidoo Rajen N, Mentz Graciela, Batterman Stuart, Robins Thomas G
Abstract excerpt
BACKGROUND: The study of gene-environment interactions enables us to further understand the pathogenesis of asthma and inflammation. The TNF-α gene has been associated with airway pathology in asthma but there is limited information in relation to pollutant exposure and the TNF-α 308G/A polymorphism. OBJECTIVE: To determine the risk conferred by the TNF-α 308(G/A) polymorphism on respiratory outcome and to...
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