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Article

Suppression of HIV type 1 replication by a dominant-negative Ets-1 mutant.

AIDS research and human retroviruses - 10 Dec 2000

Posada R, Pettoello-Mantovani M, Sieweke M, Graf T, Goldstein H

Abstract excerpt

Activity of the distal region of the human immunodeficiency virus (HIV-1) long terminal repeat (LTR), which contains binding sites for the Ets-1 and USF-1 proteins, is integral for HIV-1 replication. The Ets-1 and USF-1 proteins play a critical role in the activity of the HIV-1 LTR distal enhancer region, as indicated by the potent dominant negative effect of a mutant Ets-1 lacking trans-activation domains on the...

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Share to Genetic Vectors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11153081
DOI: 10.1089/088922200750054710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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