Article
Drosophila Pax-6/eyeless is essential for normal adult brain structure and function.
Journal of neurobiology - 5 Feb 2001
Callaerts P, Leng S, Clements J, Benassayag C, Cribbs D, Kang Y Y, Walldorf U, Fischbach K F, Strauss R
Abstract excerpt
A role for the Pax-6 homologue eyeless in adult Drosophila brain development and function is described. eyeless expression is detected in neurons, but not glial cells, of the mushroom bodies, the medullar cortex, the lateral horn, and the pars intercerebralis. Furthermore, severe defects in adult brain structures essential for vision, olfaction, and for the coordination of locomotion are provoked by two newly...
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