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Article

Characterization of Cell Lines Carrying Self-Replicating Hepatitis C Virus RNAs

1 Feb 2001

Abstract excerpt

Subgenomic selectable RNAs of the hepatitis C virus (HCV) have recently been shown to self-replicate to high levels in the human hepatoma cell line Huh-7 (V. Lohmann, F. Körner, J. O. Koch, U. Herian, L. Theilmann, and R. Bartenschlager, Science 285:110-113, 1999). Taking advantage of this cell culture system that allows analyses of the interplay between HCV replication and the host cell, in this study we...

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PMID: 11152498
DOI: 10.1128/jvi.75.3.1252-1264.2001

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