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Article

Subgenomic replicon derived from a cell line infected with the hepatitis C virus.

Biochemical and biophysical research communications - 10 May 2002

Kishine Hiroe, Sugiyama Kazuo, Hijikata Makoto, Kato Nobuyuki, Takahashi Hitoshi, Noshi Takeshi, Nio Yasunori, Hosaka Masahiro, Miyanari Yusuke, Shimotohno Kunitada

Abstract excerpt

Recently, cell culture systems have been established, where a hepatitis C virus (HCV) subgenomic replicon was efficiently replicated and maintained for a long period. To see whether a HCV sequence derived from HCV-infected cultured cell sequence can be used for the construction of a functional replicon, a HCV subgenomic RNA carrying a neomycin-resistant gene was constructed using the HCV genome RNA obtained from...

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Identifiers

PMID: 12051758
DOI: 10.1016/S0006-291X(02)00342-X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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