Article
Genotype-phenotype correlation in gemistocytic astrocytomas.
Neurosurgery - 1 Jan 2001
Kösel S, Scheithauer B W, Graeber M B
Abstract excerpt
OBJECTIVE: Gemistocytic astrocytomas often behave aggressively and carry the least favorable prognosis among diffuse astrocytomas. The frequency of p53 mutations has been reported to be significantly higher in the gemistocytic variant as compared with other astrocytomas. METHODS: Between 1985 and 1998, we selected 25 tumor samples from among 201 samples from patients with gemistocytic astrocytomas operated on at...
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