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Article

Alterations of the RRAS and ERCC1 genes at 19q13 in gemistocytic astrocytomas.

Journal of neuropathology and experimental neurology - 1 Oct 2014

Ohta Takashi, Kim Young-Ho, Oh Ji-Eun, Satomi Kaishi, Nonoguchi Naosuke, Keyvani Kathy, Pierscianek Daniela, Sure Ulrich, Mittelbronn Michel, Paulus Werner, Vital Anne, Yokoo Hideaki, McDonald Kerrie, Kleihues Paul, Nazaret Nicolas, Barbet Fabienne, Lachuer Joel, Ohgaki Hiroko

Abstract excerpt

Gemistocytic astrocytoma (World Health Organization grade II) is a rare variant of diffuse astrocytoma that is characterized by the presence of neoplastic gemistocytes and has a significantly less favorable prognosis. Other than frequent TP53 mutations (>80%), little is known about its molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25192052
DOI: 10.1097/NEN.0000000000000110

Genes

RRAS
ERCC1
IDH1
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25192052-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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