Article
Prognostic impact of TP53 mutations and P53 protein overexpression in supratentorial WHO grade II astrocytomas and oligoastrocytomas.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2002
Peraud Aurelia, Kreth Friedrich W, Wiestler Otmar D, Kleihues Paul, Reulen Hans-Jürgen
Abstract excerpt
PURPOSE: The purpose of this study was to analyze retrospectively timing, frequency, and prognostic impact of TP53 mutations and P53 protein accumulation in supratentorial WHO grade II astrocytomas and oligoastrocytomas of adult patients. EXPERIMENTAL DESIGN: We included 159 consecutively treated patients (1991-1998), and each tumor was screened for TP53 mutations and P53 protein overexpression. Prognostic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
