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Article

Independent anchoring and assembly mechanisms of INAD signaling complexes in Drosophila photoreceptors.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jan 2001

Tsunoda S, Sun Y, Suzuki E, Zuker C

Abstract excerpt

In Drosophila photoreceptors the multivalent PDZ protein INAD organizes the phototransduction cascade into a macromolecular signaling complex containing the effector PLC, the light-activated TRP channels, and a regulatory PKC. Previously, we showed that the subcellular localization of INAD signaling complexes is critical for signaling. Now we have examined how INAD complexes are anchored and assembled in...

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Identifiers

PMID: 11150331
PMCID: PMC6762460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Independent anchoring and assembly mechanisms of INAD signaling complexes in Drosophila photoreceptors.PMID 11150331Read ↗

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Assembly of the Drosophila phototransduction cascade into a signalling complex shapes elementary responses.Semantic proximity Read ↗

Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex.Semantic proximity Read ↗

A forward genetic screen in Drosophila melanogaster to identify mutations affecting INAD localization in photoreceptor cells.Semantic proximity Read ↗

Functional INAD complexes are required to mediate degeneration in photoreceptors of the Drosophila rdgA mutant.Semantic proximity Read ↗

Termination of phototransduction requires binding of the NINAC myosin III and the PDZ protein INAD.Semantic proximity Read ↗

Phospholipase C and termination of G-protein-mediated signalling in vivo.Semantic proximity Read ↗

Interaction of eye protein kinase C and INAD in Drosophila. Localization of binding domains and electrophysiological characterization of a loss of association in transgenic flies.Semantic proximity Read ↗

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