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Article

Termination of phototransduction requires binding of the NINAC myosin III and the PDZ protein INAD.

Nature neuroscience - 1 May 1999

Wes P D, Xu X Z, Li H S, Chien F, Doberstein S K, Montell C

Abstract excerpt

Many of the proteins that are critical for Drosophila phototransduction assemble into a signaling complex, signalplex, through association with the PDZ-domain protein INAD. Some of these proteins depend on INAD for proper subcellular localization to the phototransducing organelle, the rhabdomere, making it difficult to assess any physiological function of this signaling complex independent of localization. Here...

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PMID: 10321249
DOI: 10.1038/8116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Termination of phototransduction requires binding of the NINAC myosin III and the PDZ protein INAD.PMID 10321249Read ↗

A forward genetic screen in Drosophila melanogaster to identify mutations affecting INAD localization in photoreceptor cells.Semantic proximity Read ↗

Independent anchoring and assembly mechanisms of INAD signaling complexes in Drosophila photoreceptors.Semantic proximity Read ↗

A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade.Semantic proximity Read ↗

Assembly of the Drosophila phototransduction cascade into a signalling complex shapes elementary responses.Semantic proximity Read ↗

Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex.Semantic proximity Read ↗

Light-dependent phosphorylation of the Drosophila inactivation no afterpotential D (INAD) scaffolding protein at Thr170 and Ser174 by eye-specific protein kinase C.Semantic proximity Read ↗

PDA (prolonged depolarizing afterpotential)-defective mutants: the story of nina's and ina's--pinta and santa maria, too.Semantic proximity Read ↗

Role of the ninaC proteins in photoreceptor cell structure: ultrastructure of ninaC deletion mutants and binding to actin filaments.Semantic proximity Read ↗

Distinct roles of the Drosophila ninaC kinase and myosin domains revealed by systematic mutagenesis.Semantic proximity Read ↗

The Calliphora rpa mutant lacks the PDZ domain-assembled INAD signalling complex.Semantic proximity Read ↗

Light-dependent translocation of visual arrestin regulated by the NINAC myosin III.Semantic proximity Read ↗

Phospholipase C and termination of G-protein-mediated signalling in vivo.Semantic proximity Read ↗

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