Article
A forward genetic screen in Drosophila melanogaster to identify mutations affecting INAD localization in photoreceptor cells.
Fly - 1 Jan 2000
Sanxaridis Parthena D, Tsunoda Susan
Abstract excerpt
In Drosophila photoreceptors, the multivalent PDZ protein INAD interacts with multiple signaling components and localizes complexes to the rhabdomere, a subcellular compartment specialized for phototransduction. Since this localization is critical for signaling, we conducted a genetic screen of the third chromosome for mutations that result in mislocalization of an INAD-GFP fusion protein. We identified seven...
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