Article
IL-2 independent transformation of a unique human T cell line, TY8-3, and its subclones by HTLV-I and -II.
International journal of cancer - 1 Jan 2001
Yoshida T, Miyagawa E, Yamaguchi K, Kobayashi S, Takahashi Y, Yamashita A, Miura H, Itoyama Y, Yamamoto N
Abstract excerpt
Human T cell leukemia virus type I (HTLV-I) is etiologically associated with adult T cell leukemia (ATL) and chronic neurological disease, tropical spastic paraparesis (TSP). In our study, a unique IL-2 dependent human T cell line, designated TY8-3, was established from a thymoma obtained from a myasthenia gravis patient. The cells were heterogeneous and mainly consisted of those with CD4 , CD8 as well as...
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