Article
Phenotypic and functional analysis of γδ T cells in the pathogenesis of human T-cell lymphotropic virus type 1 infection.
Frontiers in immunology - 1 Jan 2022
Ruggieri Matias, Ducasa Nicolás, Juraske Claudia, Polo Virginia Gonzalez, Berini Carolina, Quiroga Maria Florencia, Christopoulos Petros, Minguet Susana, Biglione Mirna, Schamel Wolfgang W
Abstract excerpt
The human T-cell leukemia virus type 1 (HTLV-1) is the cause of serious malignant and inflammatory diseases, including adult T-cell leukemia and lymphoma and tropical spastic paraparesis. The potential protective role of γδ T cells in HTLV-1 infection remains unclear. Here, demonstrate that there is a decrease in the amount of Vγ9Vδ2 T cells in patients with HTLV-1, especially in those with HTLV-1 associated...
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