Article
Novel interleukin-2 dependent T-cell line derived from adult T-cell leukemia not associated with human T-cell leukemia virus type I.
Japanese journal of cancer research : Gann - 1 Apr 1993
Kagami Y, Tobinai K, Kinoshita T, Nagai H, Hotta T, Seto M, Ueda R, Saito H
Abstract excerpt
A novel interleukin-2 (IL-2)-dependent T-cell line, WHN2, was established from a patient with adult T-cell leukemia (ATL) not associated with human T-cell leukemia virus type I (HTLV-I). Neither the original leukemic cells nor the WHN2 cells showed proviral integration in their cellular DNAs by S...
Topics
- Aged
- Antibodies
- Antigens, Surface
- Base Sequence
- Cell Division
- DNA, Viral
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Human T-lymphotropic virus 1
- Humans
- Interleukin-2
- Karyotyping
- Leukemia, T-Cell
- Leukemia-Lymphoma, Adult T-Cell
- Leukocytes, Mononuclear