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Article

Novel interleukin-2 dependent T-cell line derived from adult T-cell leukemia not associated with human T-cell leukemia virus type I.

Japanese journal of cancer research : Gann - 1 Apr 1993

Kagami Y, Tobinai K, Kinoshita T, Nagai H, Hotta T, Seto M, Ueda R, Saito H

Abstract excerpt

A novel interleukin-2 (IL-2)-dependent T-cell line, WHN2, was established from a patient with adult T-cell leukemia (ATL) not associated with human T-cell leukemia virus type I (HTLV-I). Neither the original leukemic cells nor the WHN2 cells showed proviral integration in their cellular DNAs by Southern blot analysis. The surface phenotype showed that both the original leukemic cells and the WHN2 cells had a...

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Identifiers

PMID: 8390425
DOI: 10.1111/j.1349-7006.1993.tb00146.x
PMCID: PMC5919300

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