Article
IL-2-dependent HTLV-I-infected T cells escape from non-specific, MHC-unrestricted cellular cytotoxicity.
Clinical immunology and immunopathology - 1 Nov 1994
Plotnicky H, Cyblat D, Vernant J C, Desgranges C
Abstract excerpt
The susceptibility of NK cell-mediated cytolysis was compared between 5 human HTLV-I-transformed T cell lines and 10 newly established IL-2-dependent HTLV-I-infected lines. None of the cell lines were killed after 4 hr incubation with normal PBMC. However, after 20 hr, 3 HTLV-I-transformed lines...
Topics
- Antibody-Dependent Cell Cytotoxicity
- Cell Line
- Cytotoxicity, Immunologic
- HTLV-I Infections
- Humans
- Interleukin-2
- Killer Cells, Lymphokine-Activated
- Killer Cells, Natural
- Leukemia, T-Cell
- Major Histocompatibility Complex
- Paraparesis, Tropical Spastic
- Phenotype
- T-Lymphocytes