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Article

Characterization of T cells immortalized by Tax1 of human T-cell leukemia virus type 1.

Blood - 1 Dec 1995

Akagi T, Ono H, Shimotohno K

Abstract excerpt

Peripheral blood T cells were immortalized in vitro by introduction of the Tax1 gene of human T-cell leukemia virus type 1 (HTLV-1) with a retroviral vector and were characterized for transformation-associated markers. Long-term observation showed that these Tax1-immortalized T cells eventually exhibited very similar features that were characteristic of HTLV-1-immortalized T cells, ie, increased expression of...

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PMID: 7492783

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Characterization of T cells immortalized by Tax1 of human T-cell leukemia virus type 1.PMID 7492783Read ↗

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