Characterization of T cells immortalized by Tax1 of human T-cell leukemia virus type 1.

Article

Characterization of T cells immortalized by Tax1 of human T-cell leukemia virus type 1.

Blood - 1 Dec 1995

Akagi T, Ono H, Shimotohno K

Abstract excerpt

Peripheral blood T cells were immortalized in vitro by introduction of the Tax1 gene of human T-cell leukemia virus type 1 (HTLV-1) with a retroviral vector and were characterized for transformation-associated markers. Long-term observation showed that these Tax1-immortalized T cells eventually e...

Topics

Antigens, Differentiation
Cell Division
Cell Membrane
Cell Transformation, Viral
Clone Cells
Gene Expression
Genes, pX
Genetic Vectors
Human T-lymphotropic virus 1
Humans
Interleukin-2
Phenotype
Retroviridae
T-Lymphocytes
Time Factors

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