Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Guidance of cell migration by EGF receptor signaling during Drosophila oogenesis.

Science (New York, N.Y.) - 5 Jan 2001

Duchek P, Rørth P

Abstract excerpt

Directed cell migration is important for many aspects of normal animal development, but little is known about how cell migrations are guided or the mechanisms by which guidance cues are translated into directed cell movement. Here we present evidence that signaling mediated by the epidermal growth factor receptor (EGFR) guides dorsal migration of border cells during Drosophila oogenesis. The transforming growth...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Insect Proteins
Share to Mitogen-Activated Protein Kinases
Share to Neuregulins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oogenesis

Share to Ovarian Follicle

Share to Proto-Oncogene Proteins c-raf

Share to Transforming Growth Factor alpha

Share to Transforming Growth Factors

Source

Identifiers

PMID: 11141565
DOI: 10.1126/science.291.5501.131

Genes

EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Guidance of cell migration by EGF receptor signaling during Drosophila oogenesis.PMID 11141565Read ↗

Sequential activation of the EGF receptor pathway during Drosophila oogenesis establishes the dorsoventral axis.Semantic proximity Read ↗

An autoregulatory cascade of EGF receptor signaling patterns the Drosophila egg.Semantic proximity Read ↗

Invasive cell migration is initiated by guided growth of long cellular extensions.Semantic proximity Read ↗

Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulins.Semantic proximity Read ↗

Glycosphingolipids control the extracellular gradient of the Drosophila EGFR ligand Gurken.Semantic proximity Read ↗

Two distinct modes of guidance signalling during collective migration of border cells.Semantic proximity Read ↗

Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration.Semantic proximity Read ↗

GAGA Regulates Border Cell Migration in Drosophila.Semantic proximity Read ↗

Drosophila-raf acts to elaborate dorsoventral pattern in the ectoderm of developing embryos.Semantic proximity Read ↗

Post-transcriptional regulation of gurken by encore is required for axis determination in Drosophila.Semantic proximity Read ↗

Combined activities of Gurken and decapentaplegic specify dorsal chorion structures of the Drosophila egg.Semantic proximity Read ↗

The Drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGF alpha-like protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.