Article
Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulins.
Genes & development - 15 Sept 1996
Schnepp B, Grumbling G, Donaldson T, Simcox A
Abstract excerpt
The activation signal from tyrosine kinase receptors, such as the epidermal growth factor receptor (EGFR), is relayed via a highly conserved intracellular pathway involving Ras, Raf, and MAPK. In Drosophila, the EGFR and components of the intracellular pathway are broadly expressed, yet receptor activation evokes tissue-specific cell responses. Extracellular events that lead to receptor activation are one...
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