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Article

Post-transcriptional regulation of gurken by encore is required for axis determination in Drosophila.

Development (Cambridge, England) - 1 Dec 1997

Hawkins N C, Van Buskirk C, Grossniklaus U, Schüpbach T

Abstract excerpt

Establishment of anterior-posterior and dorsal-ventral polarity within the Drosophila egg chamber requires signaling between the germline and the somatic cells of the ovary. The gene gurken (grk) encodes a TGFalpha-like protein that is localized within the developing oocyte and is thought to locally activate torpedo/Egfr (top/Egfr), the Drosophila homolog of the EGF receptor, which is expressed throughout the...

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Source

Identifiers

PMID: 9428416
DOI: 10.1242/dev.124.23.4801

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Post-transcriptional regulation of gurken by encore is required for axis determination in Drosophila.PMID 9428416Read ↗

The Drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGF alpha-like protein.Semantic proximity Read ↗

Encore is a member of a novel family of proteins and affects multiple processes in Drosophila oogenesis.Semantic proximity Read ↗

Combined activities of Gurken and decapentaplegic specify dorsal chorion structures of the Drosophila egg.Semantic proximity Read ↗

cornichon and the EGF receptor signaling process are necessary for both anterior-posterior and dorsal-ventral pattern formation in Drosophila.Semantic proximity Read ↗

Sequential activation of the EGF receptor pathway during Drosophila oogenesis establishes the dorsoventral axis.Semantic proximity Read ↗

Functioning of the Drosophila orb gene in gurken mRNA localization and translation.Semantic proximity Read ↗

maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA.Semantic proximity Read ↗

spn-F encodes a novel protein that affects oocyte patterning and bristle morphology in Drosophila.Semantic proximity Read ↗

Evidence for a transport-trap mode of Drosophila melanogaster gurken mRNA localization.Semantic proximity Read ↗

Efficient EGFR signaling and dorsal-ventral axis patterning requires syntaxin dependent Gurken trafficking.Semantic proximity Read ↗

Oocyte determination and the origin of polarity in Drosophila: the role of the spindle genes.Semantic proximity Read ↗

The Drosophila p38 MAPK pathway is required during oogenesis for egg asymmetric development.Semantic proximity Read ↗

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