Article
Two distinct modes of guidance signalling during collective migration of border cells.
Nature - 19 Jul 2007
Bianco Ambra, Poukkula Minna, Cliffe Adam, Mathieu Juliette, Luque Carlos M, Fulga Tudor A, Rørth Pernille
Abstract excerpt
Although directed migration is a feature of both individual cells and cell groups, guided migration has been studied most extensively for single cells in simple environments. Collective guidance of cell groups remains poorly understood, despite its relevance for development and metastasis. Neural crest cells and neuronal precursors migrate as loosely organized streams of individual cells, whereas cells of the...
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