Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural control of polyketide formation in plant-specific polyketide synthases.

Chemistry & biology - 1 Dec 2000

Jez J M, Austin M B, Ferrer J, Bowman M E, Schröder J, Noel J P

Abstract excerpt

BACKGROUND: Polyketide synthases (PKSs) generate molecular diversity by utilizing different starter molecules and by controlling the final length of the polyketide. Although exploitation of this mechanistic variability has produced novel polyketides, the structural foundation of this versatility is unclear. Plant-specific PKSs are essential for the biosynthesis of anti-microbial phytoalexins, anthocyanin floral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acyl Coenzyme A
Share to Acyltransferases
Share to Chromatography, Thin Layer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dimerization

Share to Hydrogen Bonding

Share to Mass Spectrometry

Share to Multienzyme Complexes

Share to Pyrones

Source

Identifiers

PMID: 11137815
DOI: 10.1016/s1074-5521(00)00041-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural control of polyketide formation in plant-specific polyketide synthases.PMID 11137815Read ↗

Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity.Semantic proximity Read ↗

Navigating the Fungal Polyketide Chemical Space: From Genes to MoleculesSemantic proximity Read ↗

Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates.Semantic proximity Read ↗

Structural insight into chain-length control and product specificity of pentaketide chromone synthase from Aloe arborescens.Semantic proximity Read ↗

Unravelling the functional diversity of type III polyketide synthases in fungiSemantic proximity Read ↗

A novel tunnel in mycobacterial type III polyketide synthase reveals the structural basis for generating diverse metabolites.Semantic proximity Read ↗

Combinatorialization of fungal polyketide synthase-peptide synthetase hybrid proteins.Semantic proximity Read ↗

Distinct structural elements dictate the specificity of the type III pentaketide synthase from Neurospora crassa.Semantic proximity Read ↗

POLYKETIDE SYNTHASE GENE MANIPULATION: A Structure-Function Approach in Engineering Novel AntibioticsSemantic proximity Read ↗

Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol PolyketidesSemantic proximity Read ↗

Expanding the chemical space of polyketides through structure-guided mutagenesis of Vitis vinifera stilbene synthase.Semantic proximity Read ↗

Structural rearrangements of a polyketide synthase module during its catalytic cycleSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.