Article
Two conformations of G-actin related to two conformations of F-actin.
Results and problems in cell differentiation - 1 Jan 2001
Egelman E H, Orlova A
Abstract excerpt
In summary, a number of different conformational states of F-actin have been described by several different laboratories. Crystal structures have revealed that an opening of the nucleotide-binding cleft, produced by a large rotation of subdomain 2, can occur in G-actin. We have shown that two crystal states of beta-actin, in an open and closed form, can provide a very good model for the conformational difference...
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