Article
Tropomyosin-troponin regulation of actin does not involve subdomain 2 motions.
The Journal of biological chemistry - 25 May 2001
Gerson J H, Kim E, Muhlrad A, Reisler E
Abstract excerpt
Dynamic properties of F-actin structure prompted suggestions (Squire, J. M., and Morris, E. P. (1998) FASEB J. 12, 761-771) that actin subdomain 2 movements play a role in thin-filament regulation. Using fluorescently labeled yeast actin mutants Q41C, Q41C/C374S, and D51C/C374S and azidonitrophenyl putrescine (ANP) Gln(41)-labeled alpha-actin, we monitored regulation-linked changes in subdomain 2. These actins...
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