Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A nucleotide state-sensing region on actin.

The Journal of biological chemistry - 13 Aug 2010

Kudryashov Dmitri S, Grintsevich Elena E, Rubenstein Peter A, Reisler Emil

Abstract excerpt

The nucleotide state of actin (ATP, ADP-P(i), or ADP) is known to impact its interactions with other actin molecules upon polymerization as well as with multiple actin binding proteins both in the monomeric and filamentous states of actin. Recently, molecular dynamics simulations predicted that a sequence located at the interface of subdomains 1 and 3 (W-loop; residues 165-172) changes from an unstructured loop...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to Adenosine Diphosphate
Share to Adenosine Triphosphate

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Bridged Bicyclo Compounds, Heterocyclic

Share to Microscopy, Electron

Share to Nucleotides

Share to Thiazolidines

Share to Yeasts

Source

Open in PubMed Open full text

Identifiers

PMID: 20530485
DOI: 10.1074/jbc.M110.123869
PMCID: PMC2919123

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A nucleotide state-sensing region on actin.PMID 20530485Read ↗

Structural states and dynamics of the D-loop in actin.Semantic proximity Read ↗

A change in actin conformation associated with filament instability after Pi release.Semantic proximity Read ↗

D-loop Dynamics and Near-Atomic-Resolution Cryo-EM Structure of Phalloidin-Bound F-Actin.Semantic proximity Read ↗

Mutational analysis of Ser14 and Asp157 in the nucleotide-binding site of beta-actin.Semantic proximity Read ↗

Switch I closure simultaneously promotes strong binding to actin and ADP in smooth muscle myosin.Semantic proximity Read ↗

Two conformations of G-actin related to two conformations of F-actin.Semantic proximity Read ↗

Actin-Myosin Interaction: Structure, Function and Drug Discovery.Semantic proximity Read ↗

Mechanistic Insights into the Active Site and Allosteric Communication Pathways in Human Nonmuscle Myosin-2CSemantic proximity Read ↗

Regulation of yeast actin behavior by interaction of charged residues across the interdomain cleft.Semantic proximity Read ↗

Molecular mechanisms of disease-related human β-actin mutations p.R183W and p.E364K.Semantic proximity Read ↗

Mutational analysis of arginine 177 in the nucleotide binding site of beta-actin.Semantic proximity Read ↗

Impact of salt concentration and free magnesium on human beta-cardiac myosin reveal important details about the conserved mechanochemical mechanism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.