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Article

Crystal structure of a mutant elongation factor G trapped with a GTP analogue.

FEBS letters - 15 Aug 2005

Hansson Sebastian, Singh Ranvir, Gudkov Anatoly T, Liljas Anders, Logan Derek T

Abstract excerpt

Elongation factor G (EF-G) is a G protein factor that catalyzes the translocation step in protein synthesis on the ribosome. Its GTP conformation in the absence of the ribosome is currently unknown. We present the structure of a mutant EF-G (T84A) in complex with the non-hydrolysable GTP analogue GDPNP. The crystal structure provides a first insight into conformational changes induced in EF-G by GTP. Comparison...

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Source

Identifiers

PMID: 16083884
DOI: 10.1016/j.febslet.2005.07.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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