Article
A change in actin conformation associated with filament instability after Pi release.
Proceedings of the National Academy of Sciences of the United States of America - 5 Jan 1999
Belmont L D, Orlova A, Drubin D G, Egelman E H
Abstract excerpt
The ability of actin to both polymerize into filaments and to depolymerize permits the rapid rearrangements of actin structures that are essential for actin's function in most cellular processes. Filament polarity and dynamic properties are conferred by the hydrolysis of ATP on actin filaments. R...
Topics
- Actins
- Adenosine Diphosphate
- Adenosine Triphosphate
- Beryllium
- Catalytic Domain
- Fluorides
- Image Processing, Computer-Assisted
- Models, Molecular
- Mutation
- Phosphates
- Protein Conformation
- Recombinant Proteins