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Article

The butyrylcholinesterase K variant is a protective factor for sporadic Alzheimer's disease in women.

Acta neurologica Scandinavica - 1 Dec 2000

Alvarez-Arcaya A, Combarros O, Llorca J, Sánchez-Guerra M, Berciano J, Fernández-Viadero C, Peña N

Abstract excerpt

INTRODUCTION: Recent reports indicate that the K variant of the butyrylcholinesterase (BCHE) gene may act in synergism with the epsilon4 allele of apolipoprotein E (APOE) to increase the risk of Alzheimer's disease (AD), but this is controversial. MATERIAL AND METHODS: We genotyped for the BCHE-K and APOE epsilon4 alleles in a sample of 249 AD patients and 250 controls derived from the same region in a Spanish...

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Source

Identifiers

PMID: 11125748
DOI: 10.1034/j.1600-0404.2000.102006350.x

Genes

BCHE
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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