Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset confirmed Alzheimer's disease.

doi:10.1093/hmg/6.11.1933

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Article

Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset confirmed Alzheimer's disease.

Human molecular genetics - 1 Oct 1997

Lehmann D J, Johnston C, Smith A D

Abstract excerpt

The allelic frequency of the gene for the K variant of butyrylcholinesterase (BCHE-K) was 0.17 in 74 subjects with late-onset (age > 65 years) histopathologically diagnosed Alzheimer's disease (AD), which was higher than the frequencies in 104 elderly control subjects (0.09), in 14 early-onset ca...

Topics

Age of Onset
Aged
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Butyrylcholinesterase
Genetic Variation
Genotype
Humans

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