Article
The butyrylcholinesterase gene is neither independently nor synergistically associated with late-onset AD in clinic- and community-based populations.
Neuroscience letters - 19 Jun 1998
Crawford F, Fallin D, Suo Z, Abdullah L, Gold M, Gauntlett A, Duara R, Mullan M
Abstract excerpt
The K variant of the butyrylcholinesterase gene (BChE) was recently found to occur at an increased frequency in a late onset Alzheimer's disease (AD) population, specifically in individuals carrying the epsilon4 allele of the apolipoprotein E (APOE) gene. This suggested synergy between these two...
Topics
- Aged
- Alzheimer Disease
- Apolipoprotein E4
- Apolipoproteins E
- Butyrylcholinesterase
- Community Health Centers
- Female
- Genotype
- Humans
- Male
- Odds Ratio