Article
Butyrylcholinesterase K variant and apolipoprotein E4 genes do not act in synergy in Finnish late-onset Alzheimer's disease patients.
Neuroscience letters - 26 Jun 1998
Hiltunen M, Mannermaa A, Helisalmi S, Koivisto A, Lehtovirta M, Ryynänen M, Riekkinen P, Soininen H
Abstract excerpt
Examination of the allelic frequency of the butyrylcholinesterase K (BChE-K) variant gene revealed no increase among Finnish late-onset Alzheimer's disease (AD) patients either as a whole or among a subset of AD patients carrying the epsilon4 allele of apolipoprotein E (ApoE4). In contrast, BChE-...
Topics
- Age of Onset
- Aged
- Aged, 80 and over
- Alleles
- Alzheimer Disease
- Apolipoprotein E4
- Apolipoproteins E
- Butyrylcholinesterase
- Female
- Finland
- Humans
- Linkage Disequilibrium
- Male