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Article

Genetic polymorphism and cancer risk.

Current oncology reports - 1 May 2000

Clapper M L

Abstract excerpt

Inter-individual variability in carcinogen metabolism has been attributed in part to the polymorphic expression of several phase I and II detoxification enzymes. The role of these genetic polymorphisms in cancer susceptibility has been most extensively evaluated for isozymes of cytochrome P450 (CYP1A1, CYP2D6, and CYP2E1), N-acetyltransferase (NAT1 and NAT2), glutathione S-transferase (GSTM1, GSTT1, and GSTP1),...

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Source

Identifiers

PMID: 11122850
DOI: 10.1007/s11912-000-0075-z

Genes

GSTM1
GSTP1
GSTT1
NAT1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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